Browsing by Author "Mehrotra, S."

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    Atypical mucocutaneous involvement with Leishmania donovani
    (2012) Pulimood, S.A.; Rupali, P.; Ajjampur, S.S.R.; Thomas, M.; Mehrotra, S.; Sundar, S.
    Mucocutaneous leishmaniasis has rarely been reported from India. The usual causative organisms of this infection are Leishmania braziliensis and L. tropica. Another species, L. donovani, which usually causes visceral leishmaniasis, has recently been reported to cause mucocutaneous disease in a few patients from Sri Lanka. We report two patients who had undiagnosed chronic skin lesions for several years. Skin biopsies revealed Leishmania and the species was characterized as L. donovani in both patients. There was considerable improvement in the skin lesions following treatment with liposomal amphotericin B. © The National Medical Journal of India 2012.
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    Synthesis of 1-aryl-2-mercapto-4-aryl-1,6-dihydro-1,3,5-triazine-6-thione and their latentiation products as antithyroidal agent
    (1995) Mehrotra, S.; Roychowdhury, P.K.; Pandey, K.K.; Srivastava, P.K.
    Two new 1-aryl-2-benzylmercapto-4-aryl-1,6-dihydro-1,3,5-triazine-6-thiones have been synthesized by known methods (Goerdeler et al., 1967). These triazines on treatment with thiourea as dealkylating agent, in acidic medium afforded the corresponding 1-aryl-2-mercapto-4-aryl-1,6-dihydro-1,3,5-triazine-6-thione whch on further reaction with different α, β-unsaturated carbonyl compounds and aryl-cyanamide hydrochloride afforded the related adducts. Some of these compounds show appreciable antithyroidal activity. © 1995 The Pharmaceutical Society of Korea.