Browsing by Author "Mishra, Awdhesh Kumar"

Now showing 1 - 3 of 3
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    Nano-chitosan: A novel material for glioblastoma treatment
    (Elsevier Ltd, 2022) Chopra, Hitesh; Mishra, Awdhesh Kumar; Singh, Inderbir; Mohanta, Yugal Kishore; Sharma, Rohit; Emran, Talha Bin; Bibi, Shabana
    [No abstract available]
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    Occurrence, impact on agriculture, human health, and management strategies of zearalenone in food and feed: A review
    (MDPI AG, 2021) Mahato, Dipendra Kumar; Devi, Sheetal; Pandhi, Shikha; Sharma, Bharti; Maurya, Kamlesh Kumar; Mishra, Sadhna; Dhawan, Kajal; Selvakumar, Raman; Kamle, Madhu; Mishra, Awdhesh Kumar; Kumar, Pradeep
    Mycotoxins represent an assorted range of secondary fungal metabolites that extensively occur in numerous food and feed ingredients at any stage during pre- and post-harvest conditions. Zearalenone (ZEN), a mycotoxin categorized as a xenoestrogen poses structural similarity with natural estrogens that enables its binding to the estrogen receptors leading to hormonal misbalance and numerous reproductive diseases. ZEN is mainly found in crops belonging to temperate regions, primarily in maize and other cereal crops that form an important part of various food and feed. Because of the significant adverse effects of ZEN on both human and animal, there is an alarming need for effective detection, mitigation, and management strategies to assure food and feed safety and security. The present review tends to provide an updated overview of the different sources, occurrence and biosynthetic mechanisms of ZEN in various food and feed. It also provides insight to its harmful effects on human health and agriculture along with its effective detection, management, and control strategies. Copyright: � 2021 by the authors.
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    Pharmacological properties, therapeutic potential, and legal status of Cannabis sativa L.: An overview
    (John Wiley and Sons Ltd, 2021) Kumar, Pradeep; Mahato, Dipendra Kumar; Kamle, Madhu; Borah, Rituraj; Sharma, Bharti; Pandhi, Shikha; Tripathi, Vijay; Yadav, Hardeo Singh; Devi, Sheetal; Patil, Umesh; Xiao, Jianbo; Mishra, Awdhesh Kumar
    Marijuana, or Cannabis sativa L., is a common psychoactive plant used for both recreational and medicinal purposes. In many countries, cannabis-based medicines have been legalized under certain conditions because of their immense prospects in medicinal applications. With a comprehensive insight into the prospects and challenges associated with the pharmacological use and global trade of C. sativa, this mini-review focuses on the medicinal importance of the plant and its legal status worldwide; the pharmacological compounds and its therapeutic potential along with the underlying public health concerns and future perspective are herein discussed. The existence of major compounds including ?9-tetrahydrocannabinol (?9-THC), cannabidiol, cannabinol, and cannabichromene contributes to the medicinal effects of the cannabis plant. These compounds are also involved in the treatment of various types of cancer, epilepsy, and Parkinson's disease displaying several mechanisms of action. Cannabis sativa is a plant with significant pharmacological potential. However, several aspects of the plant need an in-depth understanding of the drug mechanism and its interaction with other drugs. Only after addressing these health concerns, legalization of cannabis could be utilized to its full potential as a future medicine. � 2021 John Wiley & Sons Ltd.