Browsing by Author "Pandey N.K."
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Item Concept and role of immunomodulatory medicinal plants used in Ayurvedic health care system(EnPress Publisher, LLC, 2024) Sachin; Kumar V.; Sharma M.; Vaishnavi; Chaudhary P.; Singh S.; Sudhakar K.; Kumar B.; Pandey N.K.; Singh S.K.; Choudhary A.K.; Baghel D.S.The statement "prevention is better than cure" and its applications is not a new for Ayurvedic health care system. The statement defines the aim and objectives of Ayurvedic health care system in a nutshell "swasthasya swasthya rakshanam aaturasya vikara prashamanam". The immune system is certainly considered one of our most discreet biological systems withinside the body. Immunizations may be obtained by us actively or passively. Active immunization includes stimulating with an antigen to generate immunological defenses against a destiny exposure, rather than passive vaccination, which includes administering antibodies to someone who has already been exposed to an antigen. Both plant and animal sources produce immunomodulatory effects to boost the body�s immunological reactivity against infections by engaging the non-specific immune system. Herbal immunomodulators are substances that either activate or suppress innate and adaptive immune responses in the body. Different ailments including allergies, asthma, rheumatoid arthritis, cancer, and other infectious disorders are caused by immune system failure. Therefore, regulating the many infectious illnesses requires significant immune response modification. Global scientific study is currently focused on how various medicinal plant components might alter the immune system. Numerous Indian and "Rasayana" and medicinal plants may have immunomodulatory characteristics. Some of these plants are Tinospora cordifolia, Morus alba, Acacia catechu, Allium sativum, and Mangifera indica. There are many more that are still undiscovered and offer space for greater study. � 2024 by author(s).Item Development of V2O5@GO (1D/2D) nanohybrid based chemiresistor for low-trace of toluene(Elsevier B.V., 2024) Srivastava S.; Singh A.; Sahz M.A.; Yadav B.C.; Pandey N.K.A room temperature operated V2O5 nanorods-decorated graphene oxide (GO) nanosheets-nanocomposite based chemiresistor has been fabricated for detecting low-trace of toluene (5�60 ppm). The V2O5 nanorods were grown on GO nanosheets via hydrothermal method. The surface morphological investigation done by SEM and confirmed the decoration of V2O5 nanorods on GO nanosheets. The Rietveld refinement was performed for structural analysis of V2O5 nanorods confirmed the orthorhombic phase structure. At lowest concentration of 5 ppm, the sensor response of V2O5 @GO nanohybrid was 4.90 which was 2.84 and 3.52 times higher than pure GO and V2O5, respectively. The rapid response and recovery time at 5 ppm were observed to be 4.18 s and 5.86 s, respectively. The decoration of V2O5 nanorods on GO nanosheets increased the activated sites and formed p-n heterojunction, resulting in the enhanced sensing performance. The sensor response for the maximum concentration of 60 ppm was 36.25. Also, the V2O5@GO chemiresistor demonstrated high long-term stability and selectivity towards toluene as compared to other interfering volatile organic compounds such as, methanol, ethanol, aniline, formaldehyde, benzene, and acetone. This work opens a novel window for the development of devices that are room temperature operatable, highly sensitive and selective for rapid detection of toluene gas for its commercialization. � 2023 Elsevier B.V.Item Pharmacognostical Study and Analytical Standardization of Bhringaraja Taila: An Ayurvedic Oleaginous Medicine(Informatics Publishing Limited, 2024) Kumar P.; Singh S.; Kumar B.; Sudhakar K.; Pandey N.K.; Choudhary A.K.; Mazumder R.; Das S.; Pokhrel P.; Baghel D.S.Background: Bhringaraja Taila is an Ayurvedic classical formulation. The formulation is indicated as keshaya. The present study is structured around validating the fact of preparing the formulation with and without the addition of mineral (Gairika). Aim: The objectives of this study were to prepare and analyze Bhringaraja Taila. Method: After performing the murchanna samsakara, a specified amount of Drava, Kalka and Sneha dravyas were taken and subjected to moderate heating till the watery portion evaporated Bhringraja Taila prepared with and without Gairika. Results: The refractive index of Bhringraja Taila with and without the addition of Gairika was found to be decreased in both samples. The specific gravity and saponification values of both samples were found to be within the limit but slightly increased in the sample prepared with the addition of Gairika. The iodine value of both samples was found to be less than the limit. A decreased iodine value signifies less tendency toward rancidity. The acid value of both samples was found to be within the limit but more in the sample prepared with the addition of Gairika. The peroxide value of the sample prepared with the addition of Gairika was higher than the sample prepared without Gairika. Higher peroxide value indication of rancidity. The pH of the sample prepared with the addition of Gairika was found to be acidic and the sample prepared without the addition of Gairika was found to be basic. Conclusion: Thus considering the above fact it can be concluded that the formulation was prepared without mineral (Gairika) can be more stable but the therapeutic efficacy between the two formulation cannot be confirmed until and unless there is clinical validation. � 2024, Informatics Publishing Limited. All rights reserved.
