Browsing by Author "Singh, Jaya"

Now showing 1 - 4 of 4
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    Evaluation of salivary oxidative stress in oral lichen planus using malonaldehyde
    (Wolters Kluwer Medknow Publications, 2022) Singh, Shruti; Singh, Jaya; Biradar, Basavaprabhu; Sonam, Manjari; Chandra, Shaleen; Samadi, Fahad
    Background: Oral lichen planus is a chronic, mucocutaneous, inflammatory disease, with an unknown etiology. Reactive oxygen species and oxidative damage to the tissues might be the cause. Malonaldehyde (MDA), a low molecular weight end product of lipid peroxidation reaction is a suitable biomarker of endogenous DNA damage. monitoring the oxidant-antioxidant status of saliva may serve as an efficient marker of disease development in oral lichen planus patients. Aim and Objectives: To evaluate salivary oxidative stress in oral lichen planus subject using MDA and compare it with control subjects. Furthermore, to compare MDA levels in erosive and hypertrophic lichen planus. Materials and Methods: The current study is case-control study. Unstimulated salivary samples in the morning hours were taken from oral lichen planus subjects (n = 25) and controls subjects without any oral disease (n = 25). The saliva was centrifuged at 900 g for 10 min at a temperature of 4�C. Then, the entire filtrate was transferred to Eppendorf test tubes and frozen at-80�C until analysis. Salivary MDA was done through thiobarbituric acid reactive substance assay as per the protocol laid down by the manufacturer (Sigma Aldrich Lipid Peroxidation Assay Kit). Results: The data were expressed as the mean � standard deviation and the statistical analysis was done using Student's t-test using SPSS version 21 IBM software. The salivary level of MDA was significantly higher than that of controls (P < 0.05). Conclusion: The higher level of MDA in patients with oral lichen planus suggests that free radicals and the resulting oxidative damage may be important in the pathogenesis of oral lichen planus lesions. � 2022 Wolters Kluwer Medknow Publications. All rights reserved.
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    Influence of Silver and Copper Substitution on Structural, Dielectric, Magnetic, and Catalytic Properties of Nano-Lanthanum Ferrites
    (University of Kashan, 2022) Kolahalam, Lalitha Ammadu; Diwakar, Bhagavatula S; Viswanath, I. V. Kasi; Reddy, Venu; Jyothi, N. Krishna; Singh, Jaya
    The research paper describes the synthesis of silver, copper doped (LaXFeO3) nano lanthanum ferrites (where X = Ag, Cu, both Ag and Cu) by using the sol-gel method. Their dielectric properties, magnetic properties, and catalytic applications were studied by LCR tester and VSM (Vibrating Sample Magnetometer), UV-Vis Spectroscopy respectively. The dielectric properties were studied as a function of frequency and applied field at room temperature and also in a temperature range of 313 K to 673 K. These results confirmed that the doping of silver and copper decreases the dielectric properties due to their conducting behavior. Room temperature magnetic properties revealed the doping of copper influenced the magnetic properties. It was noticed that the magnetism of bare LaFeO3 is very low and the magnetism of La0.5Ag0.25Cu0.25FeO3 and La0.5Cu0.5FeO3has increased almost 100 times. This may be attributed to the size and shape of the nano ferrites. Also, the catalytic performance of the doped LaFeO3 nanomaterials showed better catalytic performance. The results indicated that the developed nanostructures will find applications in telecommunications � 2022. Journal of Nanostructures.All Rights Reserved
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    Oncocytoma of the parotid gland: A rare benign tumour
    (Wolters Kluwer Medknow Publications, 2023) Singh, Jaya; Chandra, Akhilesh; Srilatha, Tumpuri; Jain, Trupti; Raja, Dinesh; Agrawal, Rahul
    Oncocytomas are one of the infrequent neoplasms seen in the oral cavity accounting for less than 2% of all neoplasms in the oral cavity with less than 1% chance of malignant transformation. They affect the major salivary glands and have a female predilection. The cognisance of the unique clinical and histopathological features is very important to conclude a confirmatory diagnosis. This paper reviews a case of oncocytoma presented in our department and also elucidates the diagnostic criteria for the same. � 2023 Wolters Kluwer Medknow Publications. All rights reserved.
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    Patterns of Oral and Maxillofacial Lesions in Eastern Uttar Pradesh Region: A Retrospective Study
    (Springer, 2022) Agrawal, Rahul; Chandra, Akhilesh; Singh, Jaya; Khairnar, Mahesh R.; Jain, Trupti; Raja, Dinesh; Tumpuri, Srilatha; Naveen Kumar, P.G.
    Background: Oral and maxillofacial lesions (OMFL) consist of a various malignant and benign lesions of the oral cavity. The aim of this study was to report the details of OMFL that had been diagnosed histologically at Oral Pathology Unit of a Dental Institute of eastern UP region. Materials and Methods: Oral cavity biopsied submitted to the Oral Pathology Unit during the period from 2016 to 2021 was evaluated. Information on age, gender, and histopathologic diagnosis was analyzed. Results: A total of 1128 biopsies were examined and analyzed. Reactive lesions were the most common type (n = 267; 23.7%) of lesions diagnosed, and epithelial malignancies (n = 250; 22.2%) were second most common type of lesion followed by cystic lesions (n = 202; 17.92%), epithelial lesions (n = 141; 12.5%), and odontogenic tumors (n = 122; 10.82%). Conclusion: The results provide important information on the prevalence and distribution of OMFL in eastern UP region of India. Reactive lesions were the most common type of OMFL diagnosed. Most of the lesions were soft tissue lesions, inflammatory in origin, and benign in nature. Multicentric studies involving larger sample should be carried out to assess the pattern of oral diseases in our community leading to the overall betterment of our society. � 2022, The Association of Oral and Maxillofacial Surgeons of India.