Browsing by Author "Singh, Shruti"

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    Construing the Relationship Between Entrepreneurial Adversity and Mental Well-being of Small Business Owners During COVID-19 Outbreak: The Mediating Role of Entrepreneurial Resilience
    (Sage Publications India Pvt. Ltd, 2022) Singh, Shruti; Chakraborty, Anindita
    The purpose of this study was to look at small business owners� entrepreneurial resilience and mental well-being during adversity. This paper tries to gauge the effect of the COVID-19 pandemic on an entrepreneur�s mental wellness and how being resilient in their approach to handling uncertainties mediates and positively envisages their mental wellness. The quantitative approach was utilized to collect data and achieve the specified goal. The information was gathered from 159 small business owners in Varanasi, India. The partial least squares method was used to analyze the collected data. Future research should look for more accurate ways to measure resilience as well as personal traits that could be used to further analyze the person�entrepreneurial context fit. In order to improve the generalizability of the study�s findings, researchers can also consider perceived adversity and resilience as mediating factors, in addition to the actual adversity and resilience assessed in this study. � 2022 Fortune Institute of International Business.
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    Demystifying blockchain adoption in financial sector�A critical analysis
    (Elsevier, 2023) Singh, Shruti; Chakraborty, Anindita
    Blockchain technology has shown to be effective at verifiably transporting �data� across a decentralized network and thus is moving ahead in unswervingly plumbing the financial sector and money. It can be a catalyst for change in the world of finance and money, but the broader adoption rests on how well the technical, commercial, and public policy hurdles are addressed. Financial sector challenges if properly managed can become the blockchain potential opportunities. Blockchain is the disruptive technology with highly distinguished characteristics especially the eradication of third-party intermediaries and removal of central authorities in any transactions. However, it is impossible to assume that any technology would be immune to difficulties and threats. This article is an attempt to jot down significant usages and scopes in addition to the difficulties and problems to be addressed for successful integration to take place. � 2023 Elsevier Inc. All rights reserved.
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    Evaluation of salivary oxidative stress in oral lichen planus using malonaldehyde
    (Wolters Kluwer Medknow Publications, 2022) Singh, Shruti; Singh, Jaya; Biradar, Basavaprabhu; Sonam, Manjari; Chandra, Shaleen; Samadi, Fahad
    Background: Oral lichen planus is a chronic, mucocutaneous, inflammatory disease, with an unknown etiology. Reactive oxygen species and oxidative damage to the tissues might be the cause. Malonaldehyde (MDA), a low molecular weight end product of lipid peroxidation reaction is a suitable biomarker of endogenous DNA damage. monitoring the oxidant-antioxidant status of saliva may serve as an efficient marker of disease development in oral lichen planus patients. Aim and Objectives: To evaluate salivary oxidative stress in oral lichen planus subject using MDA and compare it with control subjects. Furthermore, to compare MDA levels in erosive and hypertrophic lichen planus. Materials and Methods: The current study is case-control study. Unstimulated salivary samples in the morning hours were taken from oral lichen planus subjects (n = 25) and controls subjects without any oral disease (n = 25). The saliva was centrifuged at 900 g for 10 min at a temperature of 4�C. Then, the entire filtrate was transferred to Eppendorf test tubes and frozen at-80�C until analysis. Salivary MDA was done through thiobarbituric acid reactive substance assay as per the protocol laid down by the manufacturer (Sigma Aldrich Lipid Peroxidation Assay Kit). Results: The data were expressed as the mean � standard deviation and the statistical analysis was done using Student's t-test using SPSS version 21 IBM software. The salivary level of MDA was significantly higher than that of controls (P < 0.05). Conclusion: The higher level of MDA in patients with oral lichen planus suggests that free radicals and the resulting oxidative damage may be important in the pathogenesis of oral lichen planus lesions. � 2022 Wolters Kluwer Medknow Publications. All rights reserved.