Browsing by Author "Singh, Virendra P."

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    Association of sleep and sleep disorders with glaucoma
    (IP Innovative Publication Pvt. Ltd., 2022) Manisha; Maurya, Rajendra Prakash; Singh, Vibha; Gupta, Ashish; Patel, Amit; Singh, Virendra P.; Patel, Eshwari; Singh, Shivangi; Anand, Kartika; Roy, Meghna
    The hormone melatonin plays a role in our natural sleep-wake cycle. Natural levels of melatonin in the blood are highest at night. Aqueous flow has a distinctive circadian rhythm, being lower at night than during the day. IOP fluctuates in a rhythmical diurnal pattern and this fluctuation is greater in eyes with glaucoma. Sleep apnoea is a type of sleep disorder breathing that causes intermittent pauses in breathing during sleep, leading to transient nocturnal hypoxia and hypercapnia. Obstructive sleep apnoea (OSA) is one of the systemic risk factors for glaucoma which causes irreversible visual field (VF) damage. � 2022 Innovative Publication, All rights reserved.
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    Dry eye disease associated with Primary Sjogren syndrome: An update
    (IP Innovative Publication Pvt. Ltd., 2021) Maurya, Rajendra P.; Singh, Vibha; Manisha; Gupta, Ashish; Singh, Virendra P.; Kumar, Amit; Yadav, Archana; Singh, Shivangi
    Primary Sj�gren�s syndrome (pSS) is a chronic, multisystem autoimmune disorder, characterized by mononuclear infiltration of exocrine glands and other organs, resulting in dry eye, dry mouth and extra glandular systemic findings. Primary Sj�gren syndrome is of particular interest to ophthalmologists as it constitutes an important differential diagnosis in conditions with dry eye disease. The ocular tests are of great importance for diagnosis and monitoring of primary sjogren�s syndrome. Also a better understanding of immunological mechanisms and molecular pathways have resulted in discovery of new therapeutics for local and systemic treatment. This article illustrates an update regarding pathogenesis, diagnosis, investigative procedures and treatment options for dry eye related to Sjogren�s syndrome. � 2021 Innovative Publication, All rights reserved.
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    Ocular disorders associated with obstructive sleep apnea: A review
    (IP Innovative Publication Pvt. Ltd., 2021) Maurya, Rajendra P.; Manisha; Singh, Vibha; Gupta, Ashish; Agarwal, Sushil Kumar; Singh, Virendra P.; Singh, Mahendra K.; Shrivastav, G.N.; Kadir, Syeed Mehbub Ul
    Recently there has been upsurge in the cases of Obstructive Sleep Apnea (OSA) with increased prevalence of obesity in the general population. It has been continuously proved that OSA and metabolic syndrome go hand in hand and hence OSA predisposes an individual to a series of cardio-vascular disorders like ischemic heart disease, myocardial infarction, arrhythmia etc. In this article we have emphasized the possibility of ocular involvement in OSA patients. Several studies have shown ocular associations like floppy eye lid syndrome, glaucoma, dry eye syndrome, papilledema, keratoconus, non-arteritic anterior ischemic optic neuropathy etc. Through this review, we would like to highlight the ophthalmological associations of OSA, their pathogenesis and outcome with the treatment of OSA. � 2021 Innovative Publication, All rights reserved.