Browsing by Author "Verma, Vivek Kumar"

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    White light-emitting, biocompatible, water-soluble metallic magnesium nanoclusters for bioimaging applications
    (Institute of Physics, 2023) Srivastava, Prachi; Verma, Vivek Kumar; Sabbarwal, Shivesh; Singh, Mamata; Sahoo, Kedar; Koch, Biplob; Kumar, Manoj
    Ultra-small (1.6 nm), water-soluble, white light-emitting (WLE), highly stable (?8 months) BSA templated metallic (Mg0) nanoclusters (fluorescent magnesium nanoclusters = FMNCs) is developed using the green and facile route. Synthesis was facilitated by the reduction of magnesium salt, where template bovine serum albumin is utilized as a reducing agent and ascorbic acid act as a capping agent to impart stability in water, thereby obtaining stabilized Mg0 nanoclusters In solution, stabilized Mg0 nanoclusters produce white light (450-620 nm with FWHM ?120 nm) upon 366 nm light excitation. This white light emission was found to have a CIE coordinate of 0.30, 0.33 [pure white light CIE (0.33, 0.33)]. Taking advantage of WLE and ultrasmall size, FMNCs were used for in vitro fluorescence imaging of HaCaT cell lines, yielding blue (? = 2.94 ns, with a relative of QY = 1.2 % w.r.t QS), green (? = 3.07 ns; relative quantum yield of 4.6% w.r.t R6G) and red (? = 0.3 ns) images. Further, incubation of FMNCs with HEK293 (Human embryonic kidney cell) and cancerous MDA-MB-231 (Breast cancer cell line) human cell lines yielded 100 % cell viability. Current work is envisioned to contribute significantly in the area of science, engineering, and nanomedicine. � 2022 IOP Publishing Ltd.