Publication:
Intracellular Zn(ii) induced turn-on fluorescence of an l-phenylalanine-derived pseudopeptide

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Date

2023

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Organic and Biomolecular Chemistry

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Royal Society of Chemistry

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Abstract

A C2 symmetric l-phenylalanine-derived pseudopeptide has been synthesized for selective and sensitive recognition of Zn(ii) ions in aqueous-organic media. The pseudopeptidic probes exhibit intracellular Zn(ii) ion-sensing capabilities as demonstrated via live-cell fluorescence studies on RAW264.7 cells. Hence, we present a bioinspired pseudopeptide for potential biological applications involving intracellular Zn(ii) ion detection. � 2023 The Royal Society of Chemistry.

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