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Infection, immunity, and vaccine development

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dc.contributor.authorSingh, Bhawana
dc.contributor.authorKumar, Awnish
dc.contributor.authorTiwari, Rahul
dc.contributor.authorChauhan, Shashi Bhushan
dc.contributor.authorSingh, Om Prakash
dc.contributor.authorSingh, Santosh K.
dc.contributor.authorGautam, Vibhav
dc.contributor.authorSundar, Shyam
dc.contributor.authorKumar, Rajiv
dc.date.accessioned2025-01-27T10:15:28Z
dc.date.available2025-01-27T10:15:28Z
dc.date.issued2022
dc.description.abstractVaccination has emerged as one of the cheapest and most important healthcare interventions, saving millions of lives in both developed and developing countries. Currently, the development of drug-resistant pathogen strains and the emergence of new human pathogens due to changes in climate and human behavior have challenged vaccinologists to develop novel strategies for the development of new and effective vaccines. While most classical vaccines were developed pragmatically without a precise understanding about how they elicit immune responses and provide protection, current advancements in the fields of immunology, microbiology, genetics, molecular biology, and host-pathogen interactions have opened new opportunities for modern vaccine development with greater impact. This impact must not only be directed against established and newly emerging pathogens but should also provide protection for immune-compromised and elderly individuals. In this chapter, we will discuss host immune responses against pathogens, basic concepts about vaccine immunology and how they mediate protection against infectious agents. We will not discuss vaccine development strategies in detail, but only overview the key consideration in vaccine development programs. � 2022 Elsevier Inc. All rights reserved.
dc.identifier.doihttps://doi.org/10.1016/B978-0-323-85941-7.00006-1
dc.identifier.isbn978-032385941-7; 978-032389786-0
dc.identifier.urihttps://dl.bhu.ac.in/ir/handle/123456789/14705
dc.publisherElsevier
dc.subjectAdaptive immunity
dc.subjectHost-pathogen interaction
dc.subjectInnate immunity
dc.subjectVaccine
dc.titleInfection, immunity, and vaccine development
dc.typeBook chapter
dspace.entity.typePublication
journal.titleSystem Vaccinology: The History, the Translational Challenges and the Future

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