Publication: The pharmakinetic facet of bioactive natural compounds
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Date
2023
Journal Title
Green Products in Food Safety
Journal ISSN
Volume Title
Publisher
Elsevier
Abstract
Since ancient times, natural products (NPs) have played a significant role in human health promotion and well-being. They serve as a broad spectrum of molecular diversity with unique molecular chemotypes and as better sources of therapeutics in the absence of viable synthetic leads. Rising health awareness, along with a large body of literature on the therapeutic advantages of phytochemicals, has resurrected the interest in plant-based bioactives in recent times. Plant-based NPs have also been used in ancient systems of medicine, including AYUSH (Ayurveda, Unani, Siddha, and homoeopathy). In the present chapter, recent scientific breakthroughs in the extraction, delivery, and discovery domains of phytochemical pharmacology (extraction methods, nanotechnology, and computational pharmaceutics) have been highlighted in the context of overcoming their major challenges. Further, various pharmaceutical activities and future possibilities for plant-derived compounds in drug development have also been discussed. � 2023 Elsevier Inc. All rights reserved.
Description
Keywords
computational pharmaceutics, drug development, nanotechnology, Natural products, pharmaceutical, phytochemicals