Publication: Recent trends of chromene syntheses
| dc.contributor.author | Das, Samarpita | |
| dc.contributor.author | Asati, Pulkit | |
| dc.contributor.author | Indurthi, Harish K. | |
| dc.contributor.author | Dash, Ashutosh Kumar | |
| dc.contributor.author | Sharma, Deepak K. | |
| dc.date.accessioned | 2025-01-28T09:38:30Z | |
| dc.date.available | 2025-01-28T09:38:30Z | |
| dc.date.issued | 2023 | |
| dc.description.abstract | 2H/4H-chromenes (2H/4H-Ch) structural scaffolds have been widely employed in the synthesis of many natural products and medicinal agents. 2H/4H-Ch have attracted considerable attention due to their various pharmacological activities, such as anticonvulsant, anticholinesterase, anticancer, anti-tuberculosis, antimicrobial, and inhibitory activity against monoamine oxidase (MAO), and anti-diabetic activities. In literature, the synthesis of 4H-chromenes was performed by one-pot Knoevenagel condensation of resorcinol, aryl aldehydes, and malononitrile in the presence of basic catalysts. Also, 2H-Ch analogs were performed by the Wittig-Horner-Emmons and Suzuki-Miyaura cross-coupling reactions. A description of recent advances in the syntheses of chromenes is presented in this chapter. The strategies for the synthesis of 2H/4H-Ch discussed in this chapter are organocatalysts, organometallic or metal catalysts, heterogeneous base catalysts, enzymatic catalysts, and green chemistry-based approaches. � 2023 Bentham Science Publishers. All rights reserved. | |
| dc.identifier.isbn | 978-981512433-0; 978-981512434-7 | |
| dc.identifier.uri | https://dl.bhu.ac.in/ir/handle/123456789/21871 | |
| dc.language.iso | en | |
| dc.publisher | Bentham Science Publishers | |
| dc.subject | 2H/4H-chromenes | |
| dc.subject | Enzymatic catalyst | |
| dc.subject | Green chemistry approaches | |
| dc.subject | Heterogeneous base catalyst | |
| dc.subject | Knoevenagel condensation | |
| dc.subject | Organo-base-catalyst | |
| dc.subject | Pharmacological activities | |
| dc.subject | Wittig-Horner-Emmons | |
| dc.title | Recent trends of chromene syntheses | |
| dc.type | Book chapter | |
| dspace.entity.type | Publication | |
| journal.title | The Role of Chromenes in Drug Discovery and Development |