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Assessment of pulp sensibility in the mature necrotic teeth using regenerative endodontic therapy with various scaffolds - Randomised clinical trial

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dc.contributor.authorMittal, Neelam
dc.contributor.authorBaranwal, Harakh C.
dc.contributor.authorKumar, Praveen
dc.contributor.authorGupta, Sakshi
dc.date.accessioned2025-01-30T06:04:12Z
dc.date.available2025-01-30T06:04:12Z
dc.date.issued2021
dc.description.abstractAim: This study aimed to evaluate and compare the possibility of regaining pulp sensibility and objectives of regeneration procedure in mature necrotic teeth using regenerative endodontics. Materials and Methods: A total of 36 mature necrotic teeth were selected and a regenerative endodontic procedure was performed. A total of four groups, each involving n = 9 teeth per group were randomly grouped as (1) periapical bleeding, (2) platelet-rich fibrin (PRF), (3) collagen, and (4) hydroxyapatite. Pulp testing and radiographic assessment of periapical healing (PH) were recorded at every 3-month interval for 1 year. Readings were compared as qualitative data using the Kruskal-Wallis test to see the inter-group significant difference. Results: Readings of pulp sensibility revealed non-significant results in all intervals. At 3 and 6 months, 22.3% in the PRF group and 11.15% in collagen group; and at 9 months, 44.4% in PRF group, 33.3% in the collagen group and 22.2% in hydroxyapatite group; and at 12-months, 66.6% in PRF, 44.4% in the collagen group, 33.3% in the hydroxyapatite group and 11.1% in the periapical bleeding group showed a positive response to the cold test. But all groups did not show a positive response to heat and electric pulp testing and showed good PH in all groups at the end of 12 months. Conclusions: The presence of sensibility to cold test is indicative of the formation of vital pulp-like tissues, which was the highest in the PRF group, followed by the collagen, hydroxyapatite and periapical bleeding groups. � 2021 Indian Journal of Dental Research Published by Wolters Kluwer - Medknow.
dc.identifier.doihttps://doi.org/10.4103/ijdr.ijdr_253_21
dc.identifier.issn9709290
dc.identifier.urihttps://dl.bhu.ac.in/ir/handle/123456789/25166
dc.publisherWolters Kluwer Medknow Publications
dc.subjectCollagen
dc.subjecthydroxyapatite
dc.subjectPRF
dc.subjectregaining pulp sensation
dc.subjectregeneration in mature teeth
dc.subjectscaffolds
dc.titleAssessment of pulp sensibility in the mature necrotic teeth using regenerative endodontic therapy with various scaffolds - Randomised clinical trial
dc.typeArticle
dspace.entity.typePublication
journal.titleIndian Journal of Dental Research
journalvolume.identifier.volume32

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