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Ethnopharmacology, Phytochemistry, and Pharmacology of Ashtanga Ghrita: an Ayurvedic Polyherbal Formulation for Neurological Disorders

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dc.contributor.authorSingh, Jyoti
dc.contributor.authorSingh, Anupriya
dc.contributor.authorSharma, Vineet
dc.contributor.authorSingh, Tryambak Deo
dc.contributor.authorSingh, Meenakshi
dc.contributor.authorGarg, Ruchika
dc.contributor.authorSharma, Rohit
dc.contributor.authorGautam, Dev Nath Singh
dc.date.accessioned2025-01-27T09:49:50Z
dc.date.available2025-01-27T09:49:50Z
dc.date.issued2022
dc.description.abstractPurpose of Review: Ayurveda�is�an�ancient�Indian�medical�system�with�unique�approaches�for the treatment of various brain disorders. Ashtanga Ghrita, a cow Ghrita-based polyherbal classical formulation, has been well defined in ancient Ayurvedic texts Ashtanga Hridya to enhance speech, intellect, and memory. The formulation contains eight potent neuroprotective herbs along with clarified cow butter and milk. The review is aimed to come up with comprehensive scientific evidence regarding the plant ingredients of Ashtanga Ghrita so that it can be used for further clinical studies as well as to treat a variety of neurological diseases. Recent Findings: The plant ingredients have been practiced since ancient times for various disorders in India as well as worldwide. The plants contain various phytochemicals including terpenes, steroids, glycosides, flavonoids, alkaloids, amino acids, fatty acids, aryl esters, and carbohydrates. The collected pharmacological evidence suggests that all the plant ingredients have neuroprotective, anxiolytic, antidepressant, antioxidant, immunomodulatory, sedative, antiproliferative, and anticonvulsant activity. Summary: Based on the collected evidence, Ashtanga Ghrita may prove to be an effective neuroprotective drug and might be useful in various neurological disorders. Further, well-designed multicentric clinical trials are required to elucidate and comprehend the therapeutic potential of the formulation. � 2022, The Author(s), under exclusive licence to Springer Nature Switzerland AG.
dc.identifier.doihttps://doi.org/10.1007/s40495-022-00300-0
dc.identifier.issn2198641X
dc.identifier.urihttps://dl.bhu.ac.in/ir/handle/123456789/13119
dc.publisherSpringer Science and Business Media Deutschland GmbH
dc.subjectAshtanga Ghrita
dc.subjectAyurveda
dc.subjectCognitive disorder
dc.subjectMedicated Ghrita
dc.subjectNeuroprotective activity
dc.titleEthnopharmacology, Phytochemistry, and Pharmacology of Ashtanga Ghrita: an Ayurvedic Polyherbal Formulation for Neurological Disorders
dc.typeReview
dspace.entity.typePublication
journal.titleCurrent Pharmacology Reports
journalvolume.identifier.volume8

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2022