To study expression profile and epigenetic modification of DNA repair genes in testicular biopsies of infertile patients with impaired spermatogenesis
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Date
2017-03-31
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Department of Molecular and Human Genetics
Abstract
The complex networking of signalling pathways like DNA damage, DNA repair, apoptosis, differentiation and proliferation, coordinates the fate of the cell at different developmental stages of spermatogenesis. An integrated DNA repair pathways exits in the human genome to repair a variety of DNA damage in somatic and germ cells.
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Major Research Project
Keywords
Spermatogenesis, DNA damage