Publication:
Emerging role of ?? T cells in protozoan infection and their potential clinical application

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dc.contributor.authorKumar, Awnish
dc.contributor.authorSingh, Bhawana
dc.contributor.authorTiwari, Rahul
dc.contributor.authorSingh, Vishal Kumar
dc.contributor.authorSingh, Siddharth Sankar
dc.contributor.authorSundar, Shyam
dc.contributor.authorKumar, Rajiv
dc.date.accessioned2025-01-27T10:06:21Z
dc.date.available2025-01-27T10:06:21Z
dc.date.issued2022
dc.description.abstract?? T cells are thymus derived heterogeneous and unconventional T- lymphocyte expressing TCR ? (V ?9) and TCR? (V?2) chain and play an important role in connecting innate and adaptive armaments of immune response. These cells can recognize wide ranges of antigens even without involvement of major histocompatibility complex and exert their biological functions by cytotoxicity or activating various types of immune cells. In recent past, ?? T cells have emerged as an important player during protozoa infection and rapidly expand after exposure with them. They have also been widely studied in vaccine induced immune response against many bacterial and protozoan infections with improved clinical outcome. In this review, we will discuss the various roles of ?? T cells in immunity against malaria and leishmaniasis, the two important protozoan diseases causing significant mortality and morbidity throughout the world. � 2022
dc.identifier.doihttps://doi.org/10.1016/j.meegid.2022.105210
dc.identifier.issn15671348
dc.identifier.urihttps://dl.bhu.ac.in/ir/handle/123456789/14079
dc.publisherElsevier B.V.
dc.subjectImmune response
dc.subjectLeishmaniasis
dc.subjectMalaria
dc.subjectProtozoan
dc.subject?? T cells
dc.titleEmerging role of ?? T cells in protozoan infection and their potential clinical application
dc.typeReview
dspace.entity.typePublication
journal.titleInfection, Genetics and Evolution
journalvolume.identifier.volume98

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