Publication: Carbon dots from an immunomodulatory plant for cancer cell imaging, free radical scavenging and metal sensing applications
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Date
2021
Journal Title
Nanomedicine
Journal ISSN
Volume Title
Publisher
Future Medicine Ltd.
Abstract
Aim: This work aimed to develop Tinospora cordifolia stem-derived carbon dots (TCSCD) for cancer cell imaging, free radical scavenging and metal sensing applications. Method: The TCSCDs were synthesized by a simple, one-step, and ecofriendly hydrothermal carbonization method and characterized for their optical properties, morphology, hydrodynamic size, surface functionality, crystallinity, stability, bacterial biocompatibility, in vitro cellular imaging, free radical scavenging and metal sensing ability. Results: The TCSCDs exhibited excellent biocompatibility with dose-dependent bioimaging results in melanoma (B16F10) and cervical cancer (SiHa) cell lines. They exerted good free radical scavenging, Fe3+ sensing, bacterial biocompatibility, photostability, colloidal dispersion stability and thermal stability. Conclusion: The results reflect the potential of TCSCDs for biomedical and pharmaceutical applications. � 2021
Description
Keywords
bioimaging, carbon dots, green synthesis, metal sensing, radical scavenging, Tinospora cordifolia