Solvent-free Approaches towards the Synthesis of Therapeutically Important Heterocycles
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Date
2024
Journal Title
Current Green Chemistry
Journal ISSN
Volume Title
Publisher
Bentham Science Publishers
Abstract
The development of synthetic methodologies to obtain a diverse range of heterocyclic scaffolds has been a very attractive area of research due to their vast therapeutic importance. Conventional approaches that require the use of organic solvents, which are generally flammable, toxic, and not eco-friendly, are replaced either with greener alternatives or by completely avoiding their use. In literature, several solvent-free methods have already been reported for the synthesis of vast varieties of organic compounds. This review focuses on the solvent-free methods developed for the synthesis of different types of nitrogen and oxygen heterocycles which have exhibited diverse therapeutic applications. � 2024 Bentham Science Publishers.
Description
Keywords
greener alternatives, Heterocycle, scaffolds, solvent free, therapeutic applications, toxic