To evaluate macular thickness and peripapillary retinal nerve fibre layer (pRNFL) thickness in primary open angle glaucoma (POAG) patients using optical coherence tomography (OCT) in semi-urban population of eastern U.P

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dc.contributor.authorTiwari D.
dc.contributor.authorGupta A.
dc.contributor.authorSharma K.
dc.contributor.authorTrivedi A.
dc.contributor.authorMaurya R.P.
dc.date.accessioned2025-01-13T07:08:52Z
dc.date.available2025-01-13T07:08:52Z
dc.date.issued2024
dc.description.abstractAim: To evaluate macular thickness and peripapillary retinal nerve fibre (pRNFL) layer thickness in primary open angle glaucoma (POAG) patients using optical coherence tomography (OCT) in semi-urban population of eastern U.P. Materials and Methods: Cross-sectional observational study carried out on 72eyes of 42 POAG patients and 72 eyes of 36 normal individuals above 40 years from January 2023 � August 2023 in eye OPD of Hind Institute of Medical Sciences, Barabanki. Best corrected visual acuity, anterior segment examination, Gonioscopy, tonometry, Central corneal thickness, perimetry, fundoscopy, peripapillary RNFL and macular thickness using OCT was done in all patients. Result: POAG patients had significantly lower mean pRNFL quadrant measurements in superior, inferior and temporal quadrants when compared with controls. 83.68 � 13.55 vs.140.01 � 4.53; p=0.001 for superior quadrant; 76.33 � 12.96 vs. 141.99 � 4.51; p=0.001 for inferior quadrant; 52.31 � 8.67 vs. 74.36 � 3.56; p=0.001 for temporal quadrant. Mean pRNFL thickness in the nasal quadrant was not found significant in our study (55.53�7.08 vs. 80.85�5.24; p=0.295). Significant differences in thickness in foveal, inferior outer, temporal inner and nasal inner sector between POAG and control patients (p<0.05) were found. Conclusion: Superior, inferior and temporal pRNFL quadrants thickness and foveal, inferior outer, temporal inner and nasal inner macular thickness were found to be the best parameters to diagnose POAG at early stage. � 2024 Author(s), Published by Innovative Publication.
dc.identifier.doi10.18231/j.ijceo.2024.011
dc.identifier.issn23951443
dc.identifier.urihttps://dl.bhu.ac.in/ir/handle/123456789/3429
dc.language.isoen
dc.publisherIP Innovative Publication Pvt. Ltd.
dc.subjectMacular thickness
dc.subjectOptical coherence tomography
dc.subjectPeripapillary retinal nerve fibre layer thickness
dc.subjectPrimary open angle glaucoma
dc.titleTo evaluate macular thickness and peripapillary retinal nerve fibre layer (pRNFL) thickness in primary open angle glaucoma (POAG) patients using optical coherence tomography (OCT) in semi-urban population of eastern U.P
dc.typeArticle
journal.titleIndian Journal of Clinical and Experimental Ophthalmology
journalvolume.identifier.volume10

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