Patterns and outcomes of late onset thyroid disturbances after COVID-19 vaccination: A report of 75 cases

Simple item page
dc.contributor.authorKaur U.
dc.contributor.authorReddy N.T.S.
dc.contributor.authorReddy J.
dc.contributor.authorKrishna D.V.V.
dc.contributor.authorDehade A.
dc.contributor.authorAgrawal N.K.
dc.date.accessioned2025-01-13T07:09:19Z
dc.date.available2025-01-13T07:09:19Z
dc.date.issued2024
dc.description.abstractIsolated cases of subacute thyroiditis exist in the early period of COVID-19 vaccination, largely after mRNA vaccines. Here we report late onset thyroid disturbances and persistent health issues in patients of thyroid disorders after COVID-19 vaccination. Seventy-five patients with post COVID-19 vaccination thyroid disturbances were identified. Among these, 41 had flare of underlying thyroid illness, majority occurring at a median time lag of 28.4 weeks since 2nd dose. Thirty-one cases of new onset hypothyroidism and three of new onset hyperthyroidism were reported, with a median time lag respectively of 17.2 and 22.6 weeks since 2nd dose. Most cases occurred after ChAdOx1-nCoV-19, which was the commonest vaccine employed in mass roll out in India. Significant improvement was observed in majority, after a median follow up of 22�26 weeks. New onset health issues persisting for ?4 weeks were reported in 37.3% and were common in individuals with history of COVID-19 before vaccine. New onset metabolic, musculoskeletal, and reproductive disorders were the common health complaints. Active monitoring is warranted for late onset adverse events after COVID-19 vaccines of all types. Larger studies with involvement of unvaccinated individuals are required to understand the incidence and causality of late onset thyroid disturbances after COVID-19 vaccines. � 2023 John Wiley & Sons Ltd.
dc.identifier.doi10.1111/tmi.13947
dc.identifier.issn13602276
dc.identifier.urihttps://dl.bhu.ac.in/ir/handle/123456789/3644
dc.language.isoen
dc.publisherJohn Wiley and Sons Inc
dc.subjectadenoviral vaccine
dc.subjectadverse events of special interest
dc.subjectCOVID-19 vaccines
dc.subjectpersistent health issues
dc.subjectthyroid disturbances
dc.titlePatterns and outcomes of late onset thyroid disturbances after COVID-19 vaccination: A report of 75 cases
dc.typeArticle
journal.titleTropical Medicine and International Health
journalvolume.identifier.volume29

Files

Collections

2024