Crosstalk between brain and the peripheral tissues
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Date
2024
Authors
Journal Title
Brain and Organ Communication: Effects of Crosstalk on Neurophysiology
Journal ISSN
Volume Title
Publisher
Elsevier
Abstract
The interaction of the brain with peripheral organs is bidirectional which comprises neuronal, neurohumoral, or endocrine signaling. The substance produced by peripheral organs modulates brain function and may bring about plasticity. The substances produced by bone, skeletal muscle, heart, adipose tissue, and many other tissues are important in the regulation of brain function and plasticity in health and disease. The substances produced by peripheral organs communicate with the brain through circumventricular organs, have their receptors on endothelial cells of brain capillaries, or diffuse in extracellular vesicles. This chapter deals in detail with brain interaction with these organs in health and disease. � 2025 Elsevier Inc. All rights reserved.
Description
Keywords
Cellular neuroscience, Clinical endocrinology, Clinical neuroscience, Nervous system, Nervous system physiology, Neurophysiology, Systems neuroscience