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Item Modulation of Nitric Oxide synthases and induction of apoptosis in hepatocellular carcinoma by fiestin(Department of Zoology, 2015-06-30) Trigun, S.KFiestin, a natural flavanol, found in many common fruits and vegetables, was evident to modulate tumor growth associated signaling cascade in HCC cells in vivo and thus provided a cellular and molecular basis of anti cancer activity of this compound. Thus, this outcome provides a base line data to (a) evaluate translational feasibility of fisetin as an effective anti-HCC therapy and (b) advocates fruits and vegetable rich diet to prevent development of HCC and other tumor growth in human subjects.