Solid-state synthesis of novel anticancer drug eutectic mixture; anticancer, physical and thermal studies

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dc.contributor.authorChaudhary S.
dc.contributor.authorRai R.N.
dc.contributor.authorMaity S.
dc.contributor.authorMaiti P.
dc.date.accessioned2025-01-13T07:03:20Z
dc.date.available2025-01-13T07:03:20Z
dc.date.issued2024
dc.description.abstractGreen, solvent-free synthesis is adopted for a new pharmaceutical drug-drug eutectic with the utmost 100% yield. The synthesized eutectic mixture is significant for anticancer activity. The mandate of clinical tests could be avoided as selected nicotinamide, salicylamide, p-aminoacetinilide and benzanilide are known drugs. The compositional behaviors and established phase diagrams infer the formation of eutectics. The thermal behaviors of eutectics are studied using DSC. Further studies of eutectics are targeted for their biological applications, particularly for cell viability and anticancer activity against SiHa cancer cells where eutectic of benzanilide-salicylamide system infers its potential applicability for anticancer activity. � 2024
dc.identifier.doi10.1016/j.matlet.2024.137255
dc.identifier.issn0167577X
dc.identifier.urihttps://dl.bhu.ac.in/ir/handle/123456789/1077
dc.language.isoen
dc.publisherElsevier B.V.
dc.subjectAnticancer activity
dc.subjectBiomaterials
dc.subjectPharmaceutical compound
dc.subjectPhase diagrams
dc.subjectThermal analysis
dc.titleSolid-state synthesis of novel anticancer drug eutectic mixture; anticancer, physical and thermal studies
dc.typeArticle
journal.titleMaterials Letters
journalvolume.identifier.volume375

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