Status of visfatin in female reproductive function under normal and pathological conditions: a mini review

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dc.contributor.authorAnnie L.
dc.contributor.authorPankaj P.P.
dc.contributor.authorKharwar R.K.
dc.contributor.authorSingh A.
dc.contributor.authorRoy V.K.
dc.date.accessioned2025-01-13T07:03:07Z
dc.date.available2025-01-13T07:03:07Z
dc.date.issued2024
dc.description.abstractAdipokines are now well-known to regulate reproduction. Visfatin is an adipokine expressed in the hypothalamus, pituitary, ovary, uterus, and placenta of different species, and since it has been found to modulate the endocrine secretion of the hypothalamus, pituitary gland and ovary, it may be considered a novel regulator of female reproduction. Although the majority of the literature explored its role in ovarian regulation, visfatin has also been shown to regulate uterine remodeling, endometrial receptivity and embryo development, and its expression in the uterus is steroid dependent. Like other adipokines, visfatin expression and levels are deregulated in pathological conditions including polycystic ovary syndrome. Thus, the present mini-review focuses on the role of visfatin in female reproduction under both physiological and pathological conditions. � The Author(s), under exclusive licence to Springer Nature B.V. 2024.
dc.identifier.doi10.1007/s11033-024-09461-1
dc.identifier.issn3014851
dc.identifier.urihttps://dl.bhu.ac.in/ir/handle/123456789/979
dc.language.isoen
dc.publisherSpringer Science and Business Media B.V.
dc.subjectInsulin-like growth factor-1
dc.subjectReproductive processes
dc.subjectSpermatogenesis
dc.subjectUterine function
dc.subjectVisfatin
dc.titleStatus of visfatin in female reproductive function under normal and pathological conditions: a mini review
dc.typeShort survey
journal.titleMolecular Biology Reports
journalvolume.identifier.volume51

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