2025

Permanent URI for this collectionhttps://dl.bhu.ac.in/bhuir/handle/123456789/62057

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  • PublicationArticle
    Investigations on structural, microstructural, dielectric and electrical conductivity of the ZnO-MWCNTs nanocomposite synthesized via sol-gel method
    (Oxford University Press, 2025) Raghvendra Pratap; Anshu Kumar Singh; Sajal Rai; Atul Kumar Mishra; Jay Singh; Rajiv Giri; Anchal Srivastava
    In our present work, we used cost effective sol-gel process to synthesize pure zinc oxide (ZnO-P), ZnO-MWCNTs nanocomposites with different MWCNTs concentrations: 5 wt.% (ZnO-5) and 10 wt.% (ZnO-10). The impact of varying concentration of MWCNTs on structural, microstructural and dielectric properties of ZnO-MWCNTs nanocomposites have been thoroughly examined. X-ray diffraction (XRD) analysis reveals that the ZnO-P possess a hexagonal wurtzite phase structure. As the concentration of MWCNTs in the ZnO increases, the peak broadening becomes more pronounced. In the Raman spectra of the ZnO nanorods, a sharp and intense peak was detected around 437 cm−1, corresponding to the high-frequency branch of the E2 mode of ZnO. ID/IG ratios for pure MWCNTs, ZnO-5 and ZnO-10 are 0.643, 0.723 and 0.840 respectively. TEM analysis shows nanorod-like structure of ZnO and SAED pattern of ZnO-MWCNTs nanocomposite confirms the structural integrity of nanocomposite material. Lattice- spacing of MWCNTs has been calculated 0.357 nm by IFFT image. The frequency dependence behaviour of the dielectric constant (ε'), dielectric loss factor (tan δ), and a.c. conductivity of ZnO-P, ZnO-5, and ZnO-10 has been measured. The dielectric properties of these samples possess behaviour consistent with the Maxwell-Wagner model and Koops phenomenological theory. The improvement in dielectric properties of ZnO-MWCNTs nanocomposites as compared to ZnO makes them a suitable candidate for energy storage applications. © 2025 The Author(s)
  • PublicationBook Chapter
    Heterostructures Based on 2D Nanomaterials for Biosensing and Imaging Applications
    (wiley, 2025) Diksha Singh; Sarita Shaktawat; Ranjana Verma; Kshitij RB Singh; Jay Singh
    Here in this study, the center of attention is specified to provide a detailed discussion about the excellent features of heterostructure-based two-dimension (2D) nanomaterials. Heterostructures based on 2D nanomaterials, and their nanocomposite displayed remarkable optical, physical, chemical, and electronic properties and these properties are utilized in encouragement of their wide-spread employment in antibacterial activity, bioimaging, catalysis, drug delivery, chemical & biosensing practices, and therapy. Innumerable 2D layered Black phosphorene and other nanomaterials likewise graphene and its derivatives, tungsten disulfide (WS2), molybdenum disulfide (MoS2), tungsten di-selenide (WSe2), and molybdenum di selenide (MoSe2), designed for the performance of the fiber optic biosensor-based improved surface plasmon resonance (SPR) study also discussed. The fast electron transfer ability of electrochemically reduced MoS2 nanosheets is responsible for its good conductivity, which can be employed for the facile detection of several biological analytes that includes detection of ascorbic acid, dopamine, glucose as well as uric acid. Here we briefly discuss the latest approach for the utilization of 2D based heterostructure nanomaterials and its derivatives for an emerging biosensor that consists of surface-enhanced Raman scattering (SERS) biosensors, surface plasmon resonance (SPR) biosensors, electrochemical biosensors and offered new possibilities intended towards the exploration of sensors and imaging application. © 2025 Scrivener Publishing LLC.
  • PublicationBook Chapter
    Introduction to nanogels: exploring the frontier of nanoscale technology
    (Elsevier, 2025) Snigdha Singh; Anand Prakash Maurya; Anurag Kumar Singh; Vivek K. Chaturvedi; Jay Singh; Amit Kumar Singh; Santosh Kumar Singh
    Drug delivery holds great promise for the development of nanogel-based platforms. Owing to their exceptional stability and efficient drug-loading capacity for both hydrophilic and hydrophobic agents, nanogels present significant opportunities for pharmaceutical innovation. As multifunctional systems, composite nanogels can deliver genes, drugs, and diagnostic agents, making them ideal platforms for multimodal theranostic applications. These nanogels can respond to various stimuli, enabling the controlled release of chemotherapy and immunotherapy drugs while reprogramming cells within the tumor microenvironment to suppress tumor growth, progression, and metastasis. Specific ligands can be attached to nanogels for active targeting to enhance drug accumulation and improve therapeutic precision, ultimately improving cancer treatment outcomes. Additionally, advanced “immune-specific” nanogels possess tumor tissue-editing capabilities, further refining targeted drug delivery. Integrating multifunctional nanogel-based delivery systems enhances the precision and effectiveness of immunotherapy and combination therapies, offering improved outcomes in tumor treatment. © 2025 Elsevier Ltd. All rights reserved.
  • PublicationBook
    Nanogels: Fundamentals to Pharmaceutical and Biomedical Applications
    (Elsevier, 2025) Anurag Kumar Singh; Vivek K. Chaturvedi; Santosh Kumar Singh; Jay Singh
    Nanogels: Fundamentals to Pharmaceutical and Biomedical Applications provides a comprehensive overview of nanogels, focusing on design principles, crosslinking methods, and therapeutic agent delivery. It covers nanogels' thermal properties, stabilization, chemical modifications, and biocompatibility. The book details biomedical applications, including bioimaging, sensing, drug delivery, and tissue engineering. It also explores in-vivo assessments, responsive therapies, and safety considerations, including toxicity, clearance mechanisms, and immunological responses, offering new insights into nanogel technology. Nanogels: Fundamentals to Pharmaceutical and Biomedical Applications offers an exciting look into this emerging area and is of particular interest to healthcare professionals and researchers working on nanocarrier-based drug delivery, focusing on porous nanogel nanocarriers. © 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.
  • PublicationEditorial
    Preface
    (Elsevier, 2025) Anurag Kumar Singh; Vivek K. Chaturvedi; Santosh Kumar Singh; Jay Singh
    [No abstract available]
  • PublicationBook Chapter
    An Overview of Industry 4.0 Applications in the Area of Nanotechnology
    (Taylor and Francis, 2025) R. K. Ratnesh; R. Kumar; Jay Singh; Ramesh Chandra
    Nanotechnology has revolutionized industries worldwide, far beyond its name. This review provides a comprehensive overview of nanotechnology applications in various contemporary industries, using the latest information from major scientific conferences. The findings reveal that nanotechnology is not limited to laboratories or small nanomedicine facilities. Instead, it has penetrated deeply into industries around the world. Companies are integrating nanotechnology to improve efficiency, design, manufacturing processes, and performance of their new products. From small-scale industries such as agriculture, food, and pharmaceuticals to large industries such as automotive, civil engineering, and environmental sectors, nanotechnology has modernized virtually every technology worldwide. Through the concerted efforts of researchers, engineers, scientists, technologists, environmentalists, and educators, sustainable growth of nano-enabled industries can be anticipated in the future. © 2026 selection and editorial matter, Ratneshwar Kumar Ratnesh, Ramesh Kumar, Jay Singh and Ramesh Chandra; individual chapters, the contributors.
  • PublicationBook
    Nanotechnology Applications for Industry 4.0
    (Taylor and Francis, 2025) R. K. Ratnesh; R. Kumar; Jay Singh; Ramesh Chandra
    This book explores the applications of nanotechnology in Industry 4.0, including how nanotechnology can be used to enhance various manufacturing processes. It discusses the use of nanotechnology in areas such as materials science, energy storage, electronics, biomedical and biotechnology, advanced computing and signal processing, and communication systems. Overall, it highlights the poten tial of these technologies to transform the manufacturing and production processes of the future. Key Features: Explores nanotechnology applications within Industry 4.0 Built on a multidisciplinary approach, it offers a robust exploration of nanotechnology applications across various domains in science and engineering Includes detailed case studies and real-world examples reflecting integration of nanotechnology in Industry 4.0 Discusses communication protocols and networks Reviews development of targeted drug delivery systems, tissue engineering, medical imaging, and diagnostic tools This book is aimed at graduate students and researchers in nanotechnology, materials science, and industrial engineering. © 2026 selection and editorial matter, Ratneshwar Kumar Ratnesh, Ramesh Kumar, Jay Singh and Ramesh Chandra; individual chapters, the contributors.
  • PublicationBook Chapter
    Use of magnetic nanomaterials as nanosensors in plant systems
    (Elsevier, 2025) Siddhima Singh; Astha Singh; Neelottma Singh; Jay Singh
    Magnetic nanoparticles (MNPs) are becoming more popular in agriculture as nanosensors because of their special magnetic qualities (superparamagnetism and magnetostriction) and adaptability. MNPs comprise magnetic elements like iron, nickel, cobalt, manganese, etc., in the form of their oxides and ferrites, which are further used as nanosensors (electrochemical nanosensors, optical nanosensors) to enhance plant production and protection. Nanosensors, which are selective transducers with a characteristic dimension of nanometers, have become crucial for the nondestructive, minimally invasive monitoring of biological processes, including plant signaling pathways and metabolism. This chapter discussed the qualities of nanosensors used in plant systems, such as plant health assessment, nutrient management, disease detection, improving plant physiology, and demonstrating the ability to increase crop production. Nanosensors are utilized to detect and reduce crop losses by delivering timely, accurate, and predictive information, which can increase agricultural output. MNPs as nanosensors are cost-effective, sensitive, and highly valuable in the field of plant systems these days. Therefore, the present chapter focuses on different MNPs used as nanosensors employed to increase quality and quantity in plant production. © 2026 Elsevier Inc. All rights reserved.
  • PublicationReview
    Exploring the Potential of 2D TMD-Based Optical Biosensors: Bridging Nanotechnology and Smart Diagnostics
    (John Wiley and Sons Inc, 2025) Seema Thapa; Himshikha Malviya; Ranjana Verma; Jay Singh
    Among various emerging 2D nanomaterials, transition metal dichalcogenides (TMDs) have garnered major recognition due to their distinct morphological and chemical features, including high surface area, tunable bandgaps, strong photoluminescence, and atomically thin structures. Their integration with optical biosensors has opened new avenues for enhancing sensor performance, offering improved sensitivity and lower detection limits compared to conventional platforms. This review covers structural and optical properties of 2D TMDs, followed by surface functionalization strategies—covalent and noncovalent—using both organic and inorganic nanomaterials to enhance biosensor functionality. The review then provides key optical detection methods such as surface plasmon resonance (SPR), evanescent wave techniques, fluorescence resonance energy transfer (FRET), label-free sensing, and signal amplification. Further, fabrication strategies for 2D TMD-based optical biosensors and methods for biomolecule immobilization are covered. Applications in protein and nucleic acid detection, cellular imaging, and environmental monitoring are highlighted in this review. Additionally, the review addresses sensor stability, reproducibility, and integration with microfluidics and lab-on-chip technologies. Finally, it explores emerging trends including multimodal sensing, the use of artificial intelligence (AI) and machine learning (ML) in biosensor data analysis, personalized sensing, and 5th and 6th generation sensing, emphasizing the transformative potential of 2D TMDs in future biosensing technologies. In addition, we highlighted the challenges and future prospects concerning structural engineering and advancement in TMDs-based optical biosensors. This review will lead researchers to explore novel detection methods, integration strategies, and progress in AI and ML-assisted 2D TMDs-based optical biosensors for personalized and high-performance sensing applications. © 2025 The Chemical Society of Japan and Wiley-VCH GmbH.
  • PublicationEditorial
    Preface
    (Elsevier, 2025) Charles O. Adetunji; Jay Singh; Kshitij RB Singh; Ravindra Pratap Singh; Shyam S. Pandey
    [No abstract available]